What is NoLith

Nephrolithiasis is medical term for a kidney stone that has formed in the kidney or urinary tract.

NoLith is a drink mix that is designed to give you the two components needed to treat and prevent kidney nephrolithiasis or kidney stone formation. These components are citrate/alkali and water intake.

Kidney Stone Basics

The cause of most kidney stones is concentrated and acidic urine that is low in citrate. Low urinary citrate increases the risk of minerals in the urine to crystalize and form kidney stones, especially when the urine is concentrated from too little fluid intake.

Other factors of kidney stone formation and growth include diet, excess body weight, some medical conditions, and certain supplements and medications.

Kidney stones can affect any part of your urinary tract — from your kidneys to your bladder.

The two components needed to treat and prevent 85% of kidney stones.

The two components needed to treat and prevent most kidney stones are:

1: Enough daily fluid intake to create 2-2.5 liters of urine per day. Enough fluid intake dilutes the stone forming concentrated urine.

2: Potassium citrate to properly alkalize your urine if it is acidic. Proper urine pH is a hallmark of stone treatment and prevention.

NoLith and the two components

A scoop of NoLith drink mix offers 30mEq of potassium citrate that mixes as a 16 oz flavorful drink to get your urine alkalized and you on your way to creating 2 -2.5 liters of daily urine.

NoLith is naturally sweetened and low calorie.

What the experts say?

In todays medical practice, the art of practicing medicine has been complemented with the science of practicing medicine.

Doctors follow scientifically backed treatment guidelines.

The most recent American and European guidelines support the use of potassium citrate with proper fluid intake for calcium oxalate, uric acid and cystine stones.

See the individual stone pages for treatment algorithms based off of the latest European Guidelines.

People with recurrent kidney stones.

Those intolerant to potassium citrate tablets.

People who prefer a drink mix over the pill burden with some regimens.

People with a family history of kidney stones.

Those with concentrated urine who need to increase fluid intake while on potassium citrate urine alkalizing therapy.

NoLith offers flexibility that potassium citrate pill form therapy doesn't.

Need more fluid intake? Add more water to your prescribed dose which makes a lighter drink mix.

Is your potassium citrate prescribed dose less than 30 mEq? Dosing can adjusted down by filling the scoop proportionally less.

Measuring urine pH

Measuring urine pH is an important factor in the proper treatment of existing kidney stones and the prevention of future kidney stones.

Data shows that optimal urine pH can differ between stone type and that going above the range can be as detrimental as going below the range.

Urine pH by stone type

If you would like more in depth information. See the individual kidney stone pages of this site for more specific information on urine pH specific to kidney stone type.

Who makes NoLith

Nephcentric is the developer of NoLith. Nephcentric focuses on unmet needs for people with electrolyte disorders, chronic kidney disease, kidney transplant, and kidney stones. The products nephcentric develops are used and trusted in the USA's best hospitals and by leading physicians.

NoLith is available in two flavors.

  • NoLith Berry Blend with 30 mEq potassium citrate per scoop which mixes with 16 ounces of water. Naturally sweetened with only 10 calories per scoop. 30 servings/scoops per bag.

    Ingredients in decending order: Tripotassium citrate monohydrate, citric acid anhydrous, L-malic acid, natural flavors, maltodextrin, calcium silicate, stevia rebaudiana leaf extract, silica, monk fruit extract.

  • NoLith Lemon Lime with 30 mEq potassium citrate per scoop which mixes with 16 ounces of water. Naturally sweetened with only 10 calories per scoop. 30 servings/scoops per bag.

    Ingredients in decending order: Tripotassium citrate monohydrate, citric acid, maltodextrin, natural flavors, L-malic acid, silica, calcium silicate, stevia rebaudiana leaf extract.
Get NoLith

Dosing NoLith

Starting dosing is typically 1 scoop (30mEq potassium citrate), mixed with 16 ounces of water.

Dosing may be adjusted up or down according to urinary pH as determined by the health care provider.

If more than 1 scoop is needed per day, doses should be separated and taken in morning and late afternoon.

If more fluid intake versus citrate is needed or desired a 1/2 scoop of NoLith offers 15mEq of potassium citrate and makes a lighter flavored drink when mixing it with 16 ounces of water.

Who should not take NoLith

NoLith is contraindicated in the following:

  • People with hyperkalemia (elevated potassium levels in the blood) or people with a condition that may predispose them to elevated potassium. This may include people with chronic kidney disease, uncontrolled diabetes, acute dehydration, strenuous exercise for those who are unconditioned, adrenal insufficiency, extensive tissue breakdown.

  • People with peptic ulcer disease.

  • People with an active urinary tract infection.

  • People with reduced kidney function.

Elevated potassium levels can increase the risk of heart rhythm abnormalities and other symptoms like muscle weakness. It can be life threatening.

NoLith is a Medical Food

Unlike pharmaceuticals and supplements a medical food, as defined in section 5(b)(3) of the Orphan Drug Act (21 U.S.C. 360ee(b)(3)), is “a food which is formulated to be consumed or administered enterally under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which distinctive nutritional requirements, based on recognized scientific principles, are established by medical evaluation.” Medical Foods, including NoLith can be purchased OTC without a prescription. NoLith is made in the USA in an FDA inspected facility under cGMP guidelines.